Schizophernia and empty sella – casual or correlated?
نویسندگان
چکیده
A male patient, 44 years old, with schizophrenia which started at the age of 18. At his last follow-up visit, laboratory tests and brain magnetic resonance imaging (MRI) were performed, revealing the presence of a sellar arachnoidocele. To our knowledge, there is only one similar case report of a set of male monozygotic triplets with schizophrenia and empty sella syndrome. High-resolution chromosome analysis found an extra band at chromosome 15p in all the triplets and their father. We performed a similar evaluation in our patient and his family to compare the results and identify new information on neuroanatomical abnormalities, hormonal alterations or genetic origins of schizophrenia.
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Isolated gonadotropin deficiency with primary empty sella: Causal or casual association?
Empty sella is a radiological-anatomical entity characterised by a sella turcica filled partially or completely with cerebrospinal fluid, leading to varying degrees of pituitary flattening. Literature reports a 5% 20% incidence of empty sella in unselected autopsies leading many to argue that it is an extreme normal variant. Endocrine dysfunction varies from 8% 25% with primary empty sella and ...
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